Studies related to Serum T3 and Ashwagandha

Efficacy And Safety Of Ashwagandha Root Extract In Subclinical Hypothyroid Patients: A Double-Blind, Randomized Placebo-Controlled Trial

Effect Increase
Values (nmol/L). Placebo: before 1.26 (0.30), after 1.22 (0.50). Ashwagandha: before 1.18 (0.27), after 1.67 (0.51)
Trial Design Randomized trial
Trial Length 1-6 months
Number of Subjects 50
Sex Both Genders
Age Range 18-29, 30-44, 45-64
Notes for this study:
In a randomized, double-blind, placebo-controlled trial, 50 participants with subclinical hypothyroidism were assigned to take 600 mg of a 100% aqueous extract of ashwagandha (5% withanolides) or placebo daily for 8 weeks.

There was a notable, statistically significant increase in T3 and T4 and a notable reduction in TGH in the ashwagandha group compared with the placebo group.

There was no notable difference between groups for adverse events.