Studies related to Serum T4 and Ashwagandha

Efficacy And Safety Of Ashwagandha Root Extract In Subclinical Hypothyroid Patients: A Double-Blind, Randomized Placebo-Controlled Trial

Effect Increase
Values (nmol/L). Placebo: before 91.80 (13.45), after 95.84 (30.82). Ashwagandha: before 93.53 (12.88), after 111.84 (14.01)
Trial Design Randomized trial
Trial Length 1-6 months
Number of Subjects 50
Sex Both Genders
Age Range 18-29, 30-44, 45-64
Notes for this study:
In a randomized, double-blind, placebo-controlled trial, 50 participants with subclinical hypothyroidism were assigned to take 600 mg of a 100% aqueous extract of ashwagandha (5% withanolides) or placebo daily for 8 weeks.

There was a notable, statistically significant increase in T3 and T4 and a notable reduction in TGH in the ashwagandha group compared with the placebo group.

There was no notable difference between groups for adverse events.