Studies related to IGF Binding Protein and Olive leaf extract

Olive (Olea Europaea L.) Leaf Polyphenols Improve Insulin Sensitivity In Middle-Aged Overweight Men: A Randomized, Placebo-Controlled, Crossover Trial

Effect Increase
Trial Design Double blind
Trial Length 1-6 months
Number of Subjects 45
Sex Male
Age Range 30-44, 45-64
Body Types Overweight
Notes for this study:
Supplementation of olive leaf extract (approximately 50mg oleuropein among other phenolics) was able to improve insulin sensitivity and both glucose and insulin after a glucose tolerance test, and appeared to increase IGF binding proteins. There was no significant influence on cardiovascular, inflammatory (aside form a slight increase in IL-6, IL-8 and TNF-a unaffected) nor lipid panels.
Funding issues for this study:
TECHNZ grant, funded 50% by a commercial partner (Comvita; produced olive leaf)