Studies related to DNA methylation and Resveratrol

Trans-resveratrol Alters Mammary Promoter Hypermethylation In Women At Increased Risk For Breast Cancer

Effect Decrease
Trial Design Double blind
Trial Length n/a
Number of Subjects 39
Sex n/a
Notes for this study:
39 post menopausal women were assigned to trans-resveratrol supplementation at 10 or 100mg daily (in two divided doses).

Methylation levels of the RASSF-1α gene decreased, and via decreased PGE(2) levels seemed to be a mechanisms of breast cancer risk reduction.