Studies related to Blood Pressure and Theanine

A Double-blind, Placebo-controlled Study Evaluating The Effects Of Caffeine And L-theanine Both Alone And In Combination On Cerebral Blood Flow, Cognition And Mood

Effect Decrease
Values Systolic (consumers). Placebo: before 115.75 ± 3.70, after 114.92 ± 3.47. Theanine: before 120.58 ± 5.07, after 119.67 ± 3.69. Caffeine: before 115.42 ± 2.90, after 119.67 ± 3.88. Combination: before 116.92 ± 3.30, after 124.50 ± 4.07. Non-consumers. Placebo: before 111.83 ± 2.87, after 114.50 ± 1.67. Theanine: before 114.58 ± 3.58, after 111.17 ± 2.94. Caffeine: before 111.08 ± 2.39, after 114.75 ± 2.47. Combination: before 113.33 ± 3.35, after 117.00 ± 2.48. Diastolic: consumers Placebo: before 76.75 ± 2.38, after 75.75 ± 3.95. Theanine: before 78.17 ± 2.00, after 82.25 ± 2.47. Caffeine: before 75.00 ± 1.62, after 83.08 ± 2.67. Combination: before 76.75 ± 2.23, after 81.83 ± 2.88. Non-consumers: Placebo: before 75.33 ± 1.51, after 75.75 ± 2.28. Theanine: before 73.25 ± 1.72, after 76.58 ± 1.75. Caffeine: before 72.33 ± 1.58, after 75.00 ± 2.56. Combination: before 72.92 ± 1.64, after 77.33 ± 1.83.
Trial Design Randomized trial
Trial Length 24 hours
Number of Subjects 24
Sex Both Genders
Age Range 18-29, 30-44
Notes for this study:
In this randomized, double-blind, crossover trial, 12 habitual and 12 non-habitual consumers of caffeine took 75 mg of caffeine, 50 mg of theanine, the combination, and placebo on different days prior to cognitive and mood assessment, which had been performed prior to the dose as well.

Oxygenated hemogoblin was increased more during the absorption period, and was reduced the most durning the cognitive testing, with the other treatments being comparable. Deoxygenated hemoglobin increased far more in the caffeine group, but only in those who weren't frequent consumers of caffeine. Theanine didn't have an apparent effect.

There weren't notable effects of theanine on serial 3 subtractions, serial 7, simple reaction time, choice reaction time, alertness, or mood. Interestingly, theanine seemed to reduce the rise of blood pressure due to caffeine.

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