| Effect | Decrease |
| Trial Design | Non-controlled trial |
| Trial Length | 2-4 Weeks |
| Number of Subjects | 17 |
| Sex | Both Genders |
Supplementation of a _centella asiatica_ extract (dosage of saponins not specified) for four weeks in persons with venous insufficiency appeared to improve the clinical state of chronic venous insufficiency as assessed by nighttime cramping and edema of the legs and altered skin trophism.
