Studies related to Anxiety and Red Clover Extract

Safety And Efficacy Of Black Cohosh And Red Clover For The Management Of Vasomotor Symptoms: A Randomized Controlled Trial

Effect Decrease
Trial Design Double blind
Trial Length 6+ Months
Number of Subjects 80
Gender Female
Age Range 45-64
Body Types Overweight, Average
Notes for this study:
Oral supplementation of 398mg red clover extract (120mg isoflavones) for the course of one year failed to improve any vasomotor (hot flash) symptoms of menopause relative to placebo, in a trial where black cohosh was minorly effective and estrogen replacement therapy highly effective.

There was a minor improvement in anxiety symptoms as assessed by the Greene Anxiety scores after 12 months, but not three.

Improvement Of Postmenopausal Depressive And Anxiety Symptoms After Treatment With Isoflavones Derived From Red Clover Extracts

Effect Decrease
Trial Design Double blind
Trial Length 1-6 months
Number of Subjects 109
Gender Female
Age Range 45-64
Notes for this study:
Symptoms of anxiety (Hospital Anxiety and Depression Scale) and depression (Zung's Self Rating Depression Scale) in menopausal women given 80mg of MF11RCE supplementation daily was able to reduce anxiety (76.9%) and depression (78.3-80.6%) relative to placebo, which declined 21.7% on average.
Funding issues for this study:
Funded by the producers of MF11RCE