Studies related to TMAO and L-Carnitine

Plasma Trimethylamine-N-oxide Following Cessation Of L-carnitine Supplementation In Healthy Aged Women

Effect Increase
Values Figure 2
Trial Design Randomized trial
Trial Length 6+ Months
Number of Subjects 18
Sex Female
Notes for this study:
Eighteen female participants visited the laboratory after 24 weeks of taking 1500 mg of L-carnitine-L-tartrate or isonitrogenous placebo per day. They returned 4 and 12 months after cessation of supplementation for more testing.

The carnitine group saw substantially higher TMAO concentrations by the end of supplementation, which reverted to the placebo levels after 4 months. There weren't statistically significant differences for blood lipids, though. Levels of immune cells weren't statistically significantly different.