| Effect | Decrease |
| Values | (pg/ml). mean and 25-75th percentile Placebo: before 71.5 (37.0, 184.25), after 93.25 (44.75, 199.75). Carnitine: before 80.0 (35.0, 130.0), after 79.0 (37.5, 126.0) |
| Trial Design | Randomized trial |
| Trial Length | 1-6 months |
| Number of Subjects | 72 |
| Sex | Female |
In a randomized, double-blind, placebo-controlled trial, 72 participants with osteoarthritis took 750 mg of l-carnitine tartrate or placebo for 8 weeks.
There was a statistically significant greater reduction in pain, IL-1-beta, and matrix metalloproteinase-1 but not 13 or c-reactive protein.
