Studies related to Oxidation of LDL and L-Carnitine

L-Carnitine Supplementation Reduces Oxidized LDL Cholesterol In Patients With Diabetes

Effect Decrease
Values Oxidized LDL cholesterol (U/L). mmol/L. Mean and SD. Placebo: before 58.0 ± 10.5, after 55.0 ± 10.3 . Carnitine: before 58.2 ± 10.4 , after 43.1 ± 10.2 .
Trial Design Randomized trial
Trial Length 1-6 months
Number of Subjects 81
Sex Both Genders
Notes for this study:
In a randomized, controlled trial, 81 participants with type 2 diabetes took 2 g of L-carnitine daily or placebo in combination with seeing a dietician and consuming a low-fat weight-loss diet for 3 months.

The primary outcome was change in lipid profile, and the carnitine group saw a greater, statistically significant improvement in total cholesterol, LDL, HDL, triglycerides, and Apolipoprotein B-100, and an increase in Apolipoprotein A1. There was a greater, statistically significant reduction in oxidized LDL cholesterol in the carnitine group, as well as a general reduction in oxidative stress.