| Effect | None |
| Values | mL/min/1.73 m2 Mean and SD. Placebo: before 101.3 ± 27.0, after 99.8 ± 26.1. Carnitine: before 97.2 ± 22.1, after 96.4 ± 22.4. |
| Trial Design | Randomized trial |
| Trial Length | n/a |
| Number of Subjects | 229 |
| Sex | Both Genders |
In a randomized, double-blind, placebo-controled trial, 229 participants with hypertension and dyslipidemic type 2 diabetes took 1000 mg of acetyl-l-carnitine twice daily in addition to simvastatin, or only simvastatin for 6 months.
The primary outcome was systolic blood pressure, and there wasn't an apparent benefit, nor for diastolic blood pressure, weight, HbA1c, insulin, insulin sensitivity, glucose disposal rate, lipid profile, or kidney function.
There weren't notable differences in adverse events.
