Studies related to Whole Body Glucose Uptake and L-Carnitine

L-carnitine Improves Glucose Disposal In Type 2 Diabetic Patients

Effect Increase
Values M. (μmol/kg/minute). Healthy. Saline: 48.66±4.73 Carnitine: 52.75±5.19 Type 2 diabetes: Saline: 35.90±5.00 Carnitine: 38.90±5.16
Trial Design Randomized trial
Trial Length 24 hours
Number of Subjects 35
Sex Both Genders
Notes for this study:
In a randomized, controlled trial, 20 healthy participants and 15 patients with type 2 diabetes took 0.28 μmole/kg/minute of l-carnitine or saline during a 2-hour euglycemic hyperinsulinemic clamp.

The carnitine group saw greater glucose update, a higher glucose oxidation rate, and greater glucose storage, the differences being statistically significant for both healthy participants and type 2 diabetics.