| Effect | Decrease |
| Values | pg/ml. Mean and SD. Placebo: before 9.83 (1.80), after 10.30 (1.56). Carnitine: before 9.82 (1.30), after 9.20 (0.91) |
| Trial Design | Randomized trial |
| Trial Length | 1-6 months |
| Number of Subjects | 72 |
| Sex | Female |
In a randomized, double-blind, placebo-controlled trial, 72 participants with osteoarthritis took 750 mg of l-carnitine tartrate or placebo for 8 weeks.
There was a statistically significant greater reduction in pain, IL-1-beta, and matrix metalloproteinase-1 but not 13 or c-reactive protein.
