Studies related to Asthma and L-Carnitine

L-carnitine Improves The Asthma Control In Children With Moderate Persistent Asthma

Effect Decrease
Values C-ACT score. Mean and SD. Placebo: before 12.8 ± 1.3 after 13.3 ± 1.4. Carnitine: before 13.4 ± 1.5, after 16.5 ± 1.7. Emergency room visits. Placebo: before 3.4 ± 1.0, after 2.6 ± 0.9. Carnitine: before 3.1 ± 1.01, after 1.5 ± 0.6. Hospital admission: Placebo: before 1.8 ± 0.7, after1.8 ± 0.6. Carnitine: before 1.5 ± 0.6, after 0.44 ± 0.5
Trial Design Randomized trial
Trial Length 6+ Months
Number of Subjects 50
Sex Both Genders
Age Range 1-6, 7-12
Notes for this study:
In a randomized, double-blind, placebo-controlled trial 50 children with asthma and 50 healthy took 350 mg of l-carnitine 3 times daily for 6 months.

The primary outcomes were lung functions and Childhood Asthma Control Test (C-ACT) score. Lung function and C-ACT saw statistically significant improvements relative to placebo. There were fewer emergency room visits, fewer hospitalizations, and there was less oral steroid use in the carnitine groups among asthmatics. Blood eosinophils were reduced more. Serum IgE declined more but the difference wasn't statistically significant.