| Effect | Decrease |
| Values | Peak flow time was significantly reduced after receiving 600 and 1200 mg of l-propionylcarnitine, but not after receiving 300 mg. |
| Trial Design | Randomized trial |
| Trial Length | 24 hours |
| Number of Subjects | 12 |
| Sex | Male |
| Age Range | 45-64, 65+ |
In this crossover study, participants with atherosclerotic arterial disease of the lower limbs received 300, 600, and 1200 mg of intravenous l-propionylcarnitine, in random order, separated by a two-day washout period. Baseline work capacity on an ergometric test was established, and then participants repeated the test at 80% of their maximum working capacity before and after receiving the l-carnitine. Peak blood flow, peak flow time, and time of hyperemia after exercise and after ischemia (induced with an occlusion cuff) were measured.
