Studies related to Symptoms of Osteoarthritis and L-Carnitine

L-Carnitine supplementation ameliorates serum tumor necrosis factor-alpha and matrix metalloproteinase-3 in knee osteoarthritis women
Effect Decrease
Values Figure 2
Trial Design Randomized trial
Trial Length 1-6 months
Number of Subjects 72
Sex Female
Age Range 30-44, 45-64
Body Types Obese, Overweight
Notes for this study:
In a randomized, double-blind, placebo-controlled trial, 72 participants with mild to moderate knee osteoarthritis took 750 mg of l-carnitine or placebo daily for 2 months. There was a statistically significant reduction in serum TNF-a and reduction in matrix metalloproteinase-3. There was also a greater improvement in the Physicians Global Assessment Of The Severity of Knee Osteoarthritis.

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