Studies related to Hyperemia and L-Carnitine

L-propionylcarnitine Effect On Postexercise And Postischemic Hyperemia In Patients Affected By Peripheral Vascular Disease

Effect Decrease
Values Halftime of hyperemia was reduced by 300, 600, and 1200 mg of l-propionylcarnitine. Total time was reduced by 600 and 1200 mg but not 300 mg.
Trial Design Randomized trial
Trial Length 24 hours
Number of Subjects 12
Sex Male
Age Range 45-64, 65+
Notes for this study:
In this crossover study, participants with atherosclerotic arterial disease of the lower limbs received 300, 600, and 1200 mg of intravenous l-propionylcarnitine, in random order, separated by a two-day washout period. Baseline work capacity on an ergometric test was established, and then participants repeated the test at 80% of their maximum working capacity before and after receiving the l-carnitine. Peak blood flow, peak flow time, and time of hyperemia after exercise and after ischemia (induced with an occlusion cuff) were measured.