Studies related to Migraine and L-Carnitine

The Effects Of Magnesium, L-carnitine, And Concurrent Magnesium-L-carnitine Supplementation In Migraine Prophylaxis

Effect Decrease
Values Migraine index. Mean and SD. Control: before 22.89±4.84 after 14.60±4.39 Magnesium: before 17.04±3.37, after 2.65±0.64 Carnitine: before 16.75±3.08, after 3.39±1.32 Combination: before 23.20±5.07, after 3.39±1.28.
Trial Design Randomized trial
Trial Length 1-6 months
Number of Subjects 133
Sex Both Genders
Age Range 18-29, 30-44, 45-64
Notes for this study:
In a randomized, single-blind, controlled trial, 133 participants with frequent migraines took 500 mg of magnesium oxide daily, 500 mg of l-carnitine, the combination, or nothing for 12 weeks.

For the number of migraine attacks per month, both magnesium and carnitine performed better than control, but the combination wasn't superior to carnitine. For days with migraines per month, they also appeared effective, but it wasn't clear if the combination was better due to the higher rate at baseline for the combination group. There was potentially a smaller benefit for severity, and the combination wasn't superior. The same was true for migraine inde