| Effect | Decrease |
| Values | Change from baseline as mean ± SD (μmol/l): Placebo (−0·59 ± 3·20) vs L-Carnitine (−3·64 ± 7·00); p = 0·03 |
| Trial Design | Randomized trial |
| Trial Length | 1-6 months |
| Number of Subjects | 60 |
| Sex | Female |
| Age Range | 18-29, 30-44 |
| Body Types | Obese, Overweight |
This randomized, double-blind, placebo-controlled trial investigated the effectiveness of L-carnitine on weight loss, and glycaemic and lipid profiles in females with polycystic ovary syndrome (PCOS).
For 12 weeks, the intervention group (n = 30) took 250 mg/day L-carnitine while the control group (n = 30) took a placebo. At the studies end, the L-carnitine saw small to moderate improvements in weight, BMI, WC, HC, and glycaemic control. It did not affect lipid profiles or free testosterone.
