Effects Of L-carnitine Supplementation On Renal Anemia In Poor Responders To Erythropoietin
| Effect | Increase |
| Trial Design | Cohort |
| Trial Length | 1-6 months |
| Number of Subjects | 14 |
| Sex | Both Genders |
| Age Range | 30-44, 45-64 |
Supplementation of 500mg L-carnitine to persons on dialysis who had low serum carnitine concentrations and a poor response to erythropoietin treatment, for three months, noted that supplementation was able to increase hematocrit significantly with 36% of persons seeing more than a 2% increase. Over the whole group, total iron binding capacity was increased alongside a decrease in ferritin.
Despite the expected reduction in L-carnitine seen in the serum of persons on dialysis and its rise in response to supplementation, red blood cell carnitine was similar between groups and unaffected by supplementation.
