Studies related to Total Iron Binding Capacity and L-Carnitine

Effects Of L-carnitine Supplementation On Renal Anemia In Poor Responders To Erythropoietin

Effect Increase
Trial Design Cohort
Trial Length 1-6 months
Number of Subjects 14
Sex Both Genders
Age Range 30-44, 45-64
Notes for this study:
Supplementation of 500mg L-carnitine to persons on dialysis who had low serum carnitine concentrations and a poor response to erythropoietin treatment, for three months, noted that supplementation was able to increase hematocrit significantly with 36% of persons seeing more than a 2% increase. Over the whole group, total iron binding capacity was increased alongside a decrease in ferritin.

Despite the expected reduction in L-carnitine seen in the serum of persons on dialysis and its rise in response to supplementation, red blood cell carnitine was similar between groups and unaffected by supplementation.