Effect | None |
Values | mg/l. mmol/l Mean and SD. Placebo: before 273.4 ± 91.39, after 422.3 ± 144.83. Carnitine: before 233.4 ± 90.36, after 362.8 ± 191.68. |
Trial Design | Randomized trial |
Trial Length | 1-7 Days |
Number of Subjects | 30 |
Sex | Both Genders |
In this randomized, single-blind, placebo-controlled pilot trial, 30 participants with metabolic syndrome took for 7 days.
The primary outcome was weight loss, and there was a statistically significant greater reduction in body mass and waist circumference, but not hip circumference. There was also a statistically significant reduction in total cholesterol, but not any other lipid measure. There was a statistically significant greater reduction in fasting insulin and GGT but not fasting glucose, insulin resistance, c-reactive protein, uric acid, free fatty acids, AST, or ALT, though many were close. The carnitine group perceived less hunger and reported less fatigue.