| Effect | Increase |
| Values | L-carnitine increased venous and arterial pyruvate levels during and after exercise. |
| Trial Design | Randomized trial |
| Trial Length | 2-4 Weeks |
| Number of Subjects | 56 |
| Sex | Both Genders |
| Age Range | 45-64 |
In the first of the two crossover studies, 20 males supplemented 2 g l-carnitine and placebo daily for 3 weeks in random order. At the end of each treatment, blood flow and ankle and brachial blood pressure were measured and a walking treadmill test was completed.
In the second of the crossover studies, an additional eight patients received 3 g IV l-carnitine plus 2 mg/kg/min for 30 minutes or placebo in random order, separated by one week. The same tests were performed in this group.
