Increases In Walking Distance In Patients With Peripheral Vascular Disease Treated With L-carnitine: A Double-blind, Cross-over Study
Notes for this study:
||L-carnitine increased venous and arterial pyruvate levels during and after exercise.
|Number of Subjects
In the first of the two crossover studies, 20 males supplemented 2 g l-carnitine and placebo daily for 3 weeks in random order. At the end of each treatment, blood flow and ankle and brachial blood pressure were measured and a walking treadmill test was completed.
In the second of the crossover studies, an additional eight patients received 3 g IV l-carnitine plus 2 mg/kg/min for 30 minutes or placebo in random order, separated by one week. The same tests were performed in this group.