L-carnitine Improves Glucose Disposal In Type 2 Diabetic Patients
| Effect | Increase |
| Values | (μmol/kg/minute). Healthy: Saline: 25.87 (61.64) Carnitine: 26.40 (63.53) Type 2 diabetes: Saline: 16.25(2.95) Carnitine: 17.61 (3.33) |
| Trial Design | Randomized trial |
| Trial Length | 24 hours |
| Number of Subjects | 35 |
| Sex | Both Genders |
In a randomized, controlled trial, 20 healthy participants and 15 patients with type 2 diabetes took 0.28 μmole/kg/minute of l-carnitine or saline during a 2-hour euglycemic hyperinsulinemic clamp.
The carnitine group saw greater glucose update, a higher glucose oxidation rate, and greater glucose storage, the differences being statistically significant for both healthy participants and type 2 diabetics.
