Studies related to DNA Damage and Garlic

Garlic Supplementation Prevents Oxidative DNA Damage In Essential Hypertension

Effect Decrease
Trial Design Cohort
Trial Length 1-6 months
Number of Subjects 40
Sex Both Genders
Age Range 30-44, 45-64
Body Types Overweight, Average
Notes for this study:
8 weeks supplementation with garlic pearls (250mg containing 2.5% garlic oil) in persons with essential hypertension or normal controls (no placebo group) noted a reduction in blood pressure in hypertensives only. The hypertensives were also hypercholesterolemic, but all changes in cholesterol and triglycerides were nonsignificant.

Superoxide and lipid peroxidation in serum were reduced in hypertensives only, and DNA damage was significantly reduced in hypertensives and only trended to be reduced in controls.