Studies related to Natural Killer Cell Content and Garlic

Aged Garlic Extract Prevents A Decline Of NK Cell Number And Activity In Patients With Advanced Cancer

Effect Increase
Trial Design Double blind
Trial Length 6+ Months
Number of Subjects 50
Gender Both Genders
Age Range 45-64, 65+
Body Types Average
Notes for this study:
In persons with inoperable tumors given either aged garlic extract (500mg daily) or placebo for six months, there was no apparent increase in quality of life associated with the garlic supplement yet an increase in both natural killer cell activity and content, although activity per cell was unchanged (so the increase in overall activity was just due to more natural killer cells).

It was noted that while 5 persons in placebo experienced a 25% decline in NK cell activity, none in the garlic group did. No increase in cortisol was noted despite an increase in control.

Supplementation With Aged Garlic Extract Improves Both NK And γδ-T Cell Function And Reduces The Severity Of Cold And Flu Symptoms: A Randomized, Double-blind, Placebo-controlled Nutrition Intervention

Effect Increase
Trial Design Double blind
Trial Length 1-6 months
Number of Subjects 120
Gender Both Genders
Age Range 18-29, 30-44, 45-64
Body Types Average
Notes for this study:
Supplementation of 2.56g of aged garlic extract to otherwise healthy persons for 90 days was associated with increases in natural killer cells and γδ-T cells in serum (2-fold and 8-fold, respectively), and this was associated with a significantly reduced risk of developing sickness and a lesser decrease in symptoms.

Glutathione in PBMCs was noted to be increased in the garlic group but not control.
Funding issues for this study:
Funded by Kyolic's producers