Short-term Dehydroepiandrosterone Treatment Increases Platelet CGMP Production In Elderly Male Subjects

Effect Increase
Trial Design Double blind
Trial Length 1-6 months
Number of Subjects 24
Sex Male
Age Range 45-64, 65+
Body Types Overweight, Average
Notes for this study:
2 months of DHEA supplements, 50mg at bedtime, was able to increase circulating levels of Platelet cyclic guanosine-monophosphate, a biomarker for Nitric Oxide.

It increased testosterone and estrogen, as well as plasminogen activating factor-1. Interestingly, DHEA also lowered LDL. Other biomarkers measured were not significantly affected.