Tauroursodeoxycholic Acid May Improve Liver And Muscle But Not Adipose Tissue Insulin Sensitivity In Obese Men And Women

Effect Increase
Trial Design Double blind
Trial Length n/a
Number of Subjects 20
Sex n/a
Notes for this study:
Insulin sensitivity was increased in obese but non-diabetic men and women after 1,750mg daily ingestion of TUDCA for 4 weeks. Muscle and liver tissue became more insulin sensitive, but adipose (fat) tissue did not. The degree of improvement was approximately 30% improvement, which rivals current anti-diabetic pharmaceuticals such as thiazolinediones and metformin.

Interestingly, no effects on serum glucose nor insulin were seen.

No significant influences on body fat or weight.