Studies related to Cholestasis and Tauroursodeoxycholic Acid

Differences In The Metabolism And Disposition Of Ursodeoxycholic Acid And Of Its Taurine-conjugated Species In Patients With Primary Biliary Cirrhosis

Effect Decrease
Trial Design Double blind
Trial Length n/a
Number of Subjects 12
Sex n/a
Notes for this study:
Over 2 months at 750mg TUDCA daily, liver enzymes decreased in the range of 48-51% in a group of persons with primary biliary cirrhosis and TUDCA was more effective than UDCA at these reductions.

Both TUDCA and UDCA increased concentrations of UDCA in the bile and improvemed the bile composition, with TUDCA being more effective due to its solubility.