Chromium Supplementation For Menstrual Cycle-related Mood Symptoms
Notes for this study:
||Figures 4 and 5
|Number of Subjects
In a randomized, double-blind, crossover trial, 6 women with premenstrual syndrome were assigned to take 400 mcg of chromium polynicotinate or placebo as an adjunct to sertraline for one cycle before crossing over to the other condition.
Funding issues for this study:
Overall it wasn't clear that there was a notable or statistically significant improvement in depression or total premenstrual symptoms.
Neither the NIMH nor Pfizer had any role in study design; the collection, analysis, and interpretation of data; the writing of the report;
or the decision to submit the paper for publication.
Authors’ efforts were supported in part by R01-MH77117 (KB), R01-MH051246
(SG), and R01-MH081837 (SG). Funding for this study was provided in the form
of an unrestricted grant from Pfizer, Inc., to Duke University for expenses incurred
by the Women’s Behavioral Health Program to support research in the treatment
of premenstrual dysphoric disorder (AS)."