Stinging Nettle Cream For Osteoarthritis

Effect Decrease
Trial Design Cohort
Trial Length n/a
Number of Subjects 23
Gender n/a
Notes for this study:
A topical cream formulation with 13.33% Stinging Nettle Root extract in a Lipobase oil-in-water emulsion was used on 23 radiology confirmed patients of osteoarthritis.

From a baseline WOMAC score of 17.22, a mean reduction of 4.17 was seen with usage of the cream; many subjects reportedly asked for continued usage of the cream.

Study was not blinded, thus placebo may contribute.

Nettle Sting Of Urtica Dioica For Joint Pain--an Exploratory Study Of This Complementary Therapy

Effect Decrease
Trial Design Uncontrolled / observational study
Trial Length n/a
Number of Subjects 18
Gender n/a
Notes for this study:
When interviewing persons using stinging nettle to alleviate symptoms of osteoarthritis, 17/18 persons reported that they found it to be beneficial.

Only side effect reported in this group was transient rashes that occurred after topical application of the leaves, that faded relatively quickly.

Nettle Sting For Chronic Knee Pain: A Randomised Controlled Pilot Study

Effect None
Trial Design Cohort
Trial Length n/a
Number of Subjects 42
Gender n/a
Notes for this study:
A single blind study used for exploratory research was used in investigating whether or not Urdica Dioica (Stinging Nettle) was effective in reducing joint pain.

The application method was to take home a pretty plant, and press the leaves into the knees that hurt for 7 seconds.

There were no significantly different effects compared to placebo (simialrily looking plant), although patients did improve via placebo and did not mind the stinging sensation of the leaves.

Randomized Controlled Trial Of Nettle Sting For Treatment Of Base-of-thumb Pain

Effect Decrease
Trial Design Double blind
Trial Length 1-7 Days
Number of Subjects 27
Gender Both Genders
Age Range 45-64, 65+
Notes for this study:
Pressing the leaves of the Urdica Dioica plant (Stinging Nettle) into the base of the thumb where pain existed in a double-blind manner (compared to another plant that was seen as inert) was more effective than placebo in reducing symptoms of osteoarthritis.