Studies related to Neutrophil Count and Colostrum

Effects Of Bovine Colostrum Supplementation On Immune Variables In Highly Trained Cyclists

Effect None
Trial Design Double blind
Trial Length 1-6 months
Number of Subjects 29
Gender Male
Age Range 18-29, 30-44
Body Types Trained, Average
Notes for this study:
Supplementation of 10g bovine colostrum (20% Immunoglobulin G) failed to influence neutrophil adhesion factors (CD89) or surface markers on NK cells or lymphocytes. The expected decrease in CD3+CD8+ T cells seen with exercise, however, was attenuated relative to whey protein control resulting in a lesser reduction in the CD4/CD8 ratio associated with intense exercise.

The increase seen in salivary IgA with colostrum failed to reach statistical significance; total IgA and IgE in serum were unaffected. Overall rates of sickness trended to be reduced, but this did not reach significance.

Bovine Colostrum Supplementation's Lack Of Effect On Immune Variables During Short-term Intense Exercise In Well-trained Athletes

Effect None
Trial Design Double blind
Trial Length 1-2 Weeks
Number of Subjects 9
Gender Male
Age Range 18-29
Body Types Trained, Average
Notes for this study:
Supplementation of colostrum at 25g daily (two doses) with a high IgG content (65g/L) for ten days in which the last two days were a glycogen depletion trial followed by an endurance trial (90m at 50% Wmax) failed to alter performance during the glycogen depletion trial (anaerobic), failed to alter immune cell changes during exercise, immunoglobulins in serum, or any measured interleukin or cytokine relative to placebo (skim milk).