Studies related to CD8 Lymphocytes and Colostrum

Effects Of Bovine Colostrum Supplementation On Immune Variables In Highly Trained Cyclists

Effect Increase
Trial Design Double blind
Trial Length 1-6 months
Number of Subjects 29
Sex Male
Age Range 18-29, 30-44
Body Types Trained, Average
Notes for this study:
Supplementation of 10g bovine colostrum (20% Immunoglobulin G) failed to influence neutrophil adhesion factors (CD89) or surface markers on NK cells or lymphocytes. The expected decrease in CD3+CD8+ T cells seen with exercise, however, was attenuated relative to whey protein control resulting in a lesser reduction in the CD4/CD8 ratio associated with intense exercise.

The increase seen in salivary IgA with colostrum failed to reach statistical significance; total IgA and IgE in serum were unaffected. Overall rates of sickness trended to be reduced, but this did not reach significance.

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