Studies related to Immunoglobulin A and Lactobacillus casei

Daily Probiotic's (Lactobacillus Casei Shirota) Reduction Of Infection Incidence In Athletes

Effect Increase
Values About 50 mg/L higher salivary IgA in treatment group (approximate - read from graph). No difference in plasma IgA.
Trial Design Randomized trial
Trial Length 1-6 months
Number of Subjects 84
Sex Both Genders
Age Range 18-29, 30-44, 45-64
Body Types Trained
Notes for this study:
84 endurance athletes were supplemented with _L. casei_ shirota (6.5 x 10^9^ CFU daily for 16 weeks) while training during the winter months. Most immunological parameters did not change except for salivary IgA levels, which increased after 8 weeks of supplementation.

The supplemented athletes experienced a decreased risk of upper respiratory tract infection (URTI) symptoms. However, the severity and duration of symptoms, if displayed, did not differ as compared to placebo.
Funding issues for this study:
Funded by Yakult Honsha, a manufacturer of probiotic milk.

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