Studies related to Neutrophil Count and Tinospora cordifolia

Immunomodulatory Effect Of Tinospora Cordifolia Extract In Human Immuno-deficiency Virus Positive Patients

Effect None
Trial Design Double blind
Trial Length 6+ Months
Number of Subjects 68
Gender Both Genders
Age Range 18-29, 30-44, 45-64
Notes for this study:
Supplementation of 300mg of a water extract of tinospora cordifolia (5% bitter principles) thrice daily for six months in persons with HIV was noted to cause a reduction in eosinophils (30%) and a modest reduction in reproted symptoms, but the main study parameter (an increase in CD4+ lymphocytes) failed to occur alongside failures in increasing neutrophil and monocyte counts.

Efficacy Of Tinospora Cordifolia In Allergic Rhinitis

Effect Decrease
Trial Design Double blind
Trial Length 1-6 months
Number of Subjects 75
Gender Both Genders
Age Range 18-29, 30-44, 45-64
Notes for this study:
Thrice daily supplementation of 300mg of a water extract of _tinospora cordifolia_ (5% bitter principles) for 8 weeks in persons suffering from allergic rhinitus was able to offer complete resolution of symptoms in 61-83% of persons (depending on parameter measured, with most efficacy against sneezing and least in regards to nasal obstruction).

Leukocytes were increased in the serum of 69% yet reduced in 25% of persons; it was not clear how large of a change this was or the reason for the differences. In nasal mucosa, neutrophils and eosinophils (57% for the latter) decreased.

Immunomodulatory Role Of Tinospora Cordifolia As An Adjuvant In Surgical Treatment Of Diabetic Foot Ulcers: A Prospective Randomized Controlled Study

Effect None
Trial Design Double blind
Trial Length 6+ Months
Number of Subjects 45
Gender Both Genders
Age Range 45-64
Notes for this study:
Supplementation of _tinospora cordifolia_ over 18 months appears to increase phagocytosis in macrophages and although there was a significantly reduced number of required debridements for diabetic foot ulcers the other measured parameters (wound depth and severity, healing rate, and global improvement) failed to reach significance.