Italian Double-blind Multicenter Study Comparing S-adenosylmethionine, Naproxen, And Placebo In The Treatment Of Degenerative Joint Disease

Effect Increase
Trial Design Double blind
Trial Length 1-6 months
Number of Subjects 734
Sex Both Genders
Age Range 45-64, 65+
Notes for this study:
1200mg SAMe after 30 days was associated with significant improvements in pain and functionality in adults with osteoarthritis. Efficacy was similar to 750mg Naproxen in regards to pain reduction and symptoms reduction over 30 days. There was efficacy in persons with hip osteoarthritis

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