Studies related to Mucus Production and Kefir

A Randomized Clinical Trial Measuring The Influence Of Kefir On Antibiotic-associated Diarrhea: The Measuring The Influence Of Kefir (MILK) Study

Effect None
Values No significant effect on "runny nose" among children taking antibiotics for an upper respiratory infection.
Trial Design Randomized trial
Trial Length 1-2 Weeks
Number of Subjects 125
Sex Both Genders
Age Range 1-6
Notes for this study:
In this preregistered trial, children who were prescribed antibiotics for upper respiratory infections received 150 mL/day of either kefir or heat-killed kefir (as placebo) for 10 days. Their parents were asked to make sure they drank at least half of the drink (75 mL) every day. There was no significant difference in the incidence of diarrhea between the two groups.

The kefir used in this study was a commercial American kefir (Probugs) containing the following probiotic bacteria: _Lactococcus lactis, Lactococcus plantarum, Lactococcus rhamnosus, Lactococcus casei, Lactococcus lactis_ subsp. _diacetylactis, Leuconostoc cremoris, Bifidobacterium longum, Bifidobacterium breve,_ and _Lactobacillus acidophilus_, and the yeast _Saccharomyces florentinus_.
Funding issues for this study:
"Funding/Support: This study was supported by Lifeway Foods, Inc.
Roles of the Sponsor: Dr Merenstein contacted Lifeway Foods, Inc, whose only role was to provide funding and product (drinks for the study), review the protocol and manuscript, and give nonbinding input.
Financial Disclosure: No authors are associated with Lifeway Foods, Inc, and the authors were responsible for developing the protocol, gathering data, supervising double data entry, and analyzing the data, and vouch for the completeness and accuracy of the data and analysis. All research personnel and statisticians were blinded throughout the study, including during initial review of data."