Studies related to and

Prolonged-release Melatonin Improves Sleep Quality And Morning Alertness In Insomnia Patients Aged 55 Years And Older And Has No Withdrawal Effects

Effect Decrease
Trial Design Double blind
Trial Length n/a
Number of Subjects 170
Gender n/a
Notes for this study:
In primary insomnia patients, 2mg of prolonged release melatonin was effective in reducing sleep latency (time to sleep) and improving sleep quality without withdrawal effects.

Prophylaxis Of Migraine With Melatonin: A Randomized Controlled Trial

Effect Decrease
Trial Design Double blind
Trial Length n/a
Number of Subjects 46
Gender n/a
Notes for this study:
Melatonin at 2mg was unable to reduce frequency and severity of migraine attacks, but improved insomnia symptoms in a subset of persons who experienced delayed sleep onset. This study has methodological flaws, expanded upon in the detailed summary

Evaluation Of Sleep, Puberty And Mental Health In Children With Long-term Melatonin Treatment For Chronic Idiopathic Childhood Sleep Onset Insomnia

Effect Decrease
Trial Design Double blind
Trial Length n/a
Number of Subjects 48
Gender n/a
Notes for this study:
Insomnia symptoms were decreased in children with insomnia, and no adverse effects were noted on childhood development

The Effect Of Prolonged-release Melatonin On Sleep Measures And Psychomotor Performance In Elderly Patients With Insomnia

Effect Decrease
Trial Design Double blind
Trial Length n/a
Number of Subjects 40
Gender n/a
Notes for this study:
Melatonin was effective in improving sleep quality and reducing symptoms of insomnia such as sleep latency. No adverse effects were noted on physical performance in the morning