Studies related to Nicotine Addiction and N-Acetylcysteine

The Role Of Cystine-glutamate Exchange In Nicotine Dependence In Rats And Humans

Effect Decrease
Trial Design Double blind
Trial Length 2-4 Weeks
Number of Subjects 29
Sex Both Genders
Notes for this study:
In a pilot but blinded study, supplementation of 2,400mg of N-acetylcysteine daily to nicotine addicted smokers (continuing nicotine administration) noted that after two weeks there was a trend to reduce the number of cigarettes smoked daily. Although the magnitude was not given (and cigarettes smoked changing based on the day of the week) the magnitude of reduction appeared to be around 25%.