| Effect | Decrease |
| Trial Design | Double blind |
| Trial Length | 1-6 months |
| Number of Subjects | 27 |
| Sex | Both Genders |
| Age Range | 30-44, 45-64 |
| Body Types | Obese |
Supplementation of extended-release niacin (500mg, titrating up to 2,000mg over three weeks) for a total of 16 weeks in obese subjects with NAFLD appeared to worsen insulin sensitivity. ApoB was not significantly reduced overall although the vLDL-ApoB complex was reduced alongside triglycerides and the vLDL-TG complex.
