Studies related to vLDL-C and Vitamin B3 (Niacin)

Effect Of Fenofibrate And Niacin On Intrahepatic Triglyceride Content, Very Low-density Lipoprotein Kinetics, And Insulin Action In Obese Subjects With Nonalcoholic Fatty Liver Disease

Effect Decrease
Trial Design Double blind
Trial Length 1-6 months
Number of Subjects 27
Sex Both Genders
Age Range 30-44, 45-64
Body Types Obese
Notes for this study:
Supplementation of extended-release niacin (500mg, titrating up to 2,000mg over three weeks) for a total of 16 weeks in obese subjects with NAFLD appeared to worsen insulin sensitivity. ApoB was not significantly reduced overall although the vLDL-ApoB complex was reduced alongside triglycerides and the vLDL-TG complex.

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