Effect | Increase |
Trial Design | Randomized trial |
Trial Length | 1-7 Days |
Number of Subjects | 18 |
Sex | Both Genders |
Age Range | 18-29, 30-44, 45-64 |
Supplementation of 1g extended release niacin for one week in subjects with low HDL cholesterol appeared to beneficially influence triglycerides to a minor degree (3-4%) without affecting HDL quantity, although particle size of HDL was decreased in both groups (5.8-6.2%; with or without laropiprant).
There appeared to be an improvement in flow-mediated vasodilation that was dependent on supplementation, as it was no longer present a week after supplementation was ceased.