The Effects Of Free Fatty Acids On Gluconeogenesis And Glycogenolysis In Normal Subjects
Effect | None |
Trial Design | Non-controlled trial |
Trial Length | 24 hours |
Number of Subjects | 12 |
Sex | Both Genders |
Age Range | 30-44 |
Body Types | Overweight |
Supplementation of niacin (100mg every 30 minutes) during a fasted state of at least 20 hours appears to cause acute increases in plasma free fatty acids and ketone bodies, with mild reductions in blood glucose and no influence on gluconeogenesis.
Insulin initially had a mild reduction, but rebounded after a full days fast. This was parallel to lipolysis rates, which initially were reduced then rebounded.