Four Weeks Of IV Iron Supplementation Reduces Perceived Fatigue And Mood Disturbance In Distance Runners
Notes for this study:
||Brunel Mood Scale. Figure 2
|Number of Subjects
In a randomized, double-blind, placebo-controlled trial, 14 distance runners without anemia but with low ferritin levels were allocated to 3 intravenous doses of 100 mg ferric-carboxymaltose or saline over 4 weeks. There was no significant difference between groups in for the 400 m time trial, or for the 10x400 m training session.
The iron group had a moderate but not statistically significant improvement compared with placebo in total mood disturbance from the Brunel Mood Scale. After 6 weeks, there was a notable, statistically significant improvement in total fatigue score in the iron group compared with the placebo group.
While the iron group didn't see an improvement in running time, the placebo group saw a greater worsening, the difference being statistically significant for the 3000 m at week 4.