Studies related to Symptoms of Schizophrenia and Folic Acid

Enhancement Of Recovery From Psychiatric Illness By Methylfolate

Effect Decrease
Values Clinician scoring of 4 (little to no improvement) to 1 (symptom-free): From 2.1 to 1.6 in 6 months with methylfolate vs. 2.5 to 2.6 placebo.
Trial Design Randomized trial
Trial Length 6+ Months
Number of Subjects 123
Sex Both Genders
Age Range 18-29, 30-44
Notes for this study:
In subjects who used supplemental methylfolate at 15mg for six months, supplementation was associated with improvements in social recovery for both depressive and schizophrenic patients; overall benefits to these two conditions appeared to be better than placebo after six months. Of note is that subjects did not have optimal folate levels in their blood at the start of the study.