An Oil Mixture With Trans-10, Cis-12 Conjugated Linoleic Acid Increases Markers Of Inflammation And In Vivo Lipid Peroxidation Compared With Cis-9, Trans-11 Conjugated Linoleic Acid In Postmenopausal Women

Effect None
Trial Design Cohort
Trial Length n/a
Number of Subjects 75
Sex n/a
Notes for this study:
CLA mix (41% c9t11, 40% t10c12) was compared against CLA Milk (85% c9t11, 7% t10c12) and oleic acid as control in 75 postmenopausal women; all at 5.5g for 16 weeks. No reported differences were noted in body weight or fat mass, but a significant relative drop in HDL cholesterol (-0.2mmol/L) relative to oleic acid was seen, and an increase (0.16mmol/L) of triglycerides was noted.

No effect on IL-6, ICAM-1, or VCAM-1 was noted. CRP was higher in the CLA mixture group relative to the CLA milk group, whereas both groups had a higher 8-iso PGF2α level relative to oleic acid (60% CLA mix, 25% CLA milk)

CLA milk group reported a lower energy intake during the study period, 87% of the CLA mix group.