Conjugated Linoleic Acid Supplementation For 8 Weeks Does Not Affect Body Composition, Lipid Profile, Or Safety Biomarkers In Overweight, Hyperlipidemic Men

Effect None
Trial Design Double blind
Trial Length 1-6 months
Number of Subjects 27
Sex Male
Age Range 30-44, 45-64
Body Types Overweight
Notes for this study:
Relative to safflower oil as a control at 3.5g daily, two experimental groups were used. 3.5g of oil comprising 2.7g of 50/50 CLA isomers, and 3.5g oil comprising 2.7g of jsut the c9t11 isomer. Population was overweight and hyperlipidemic men, and no dietary controls were in place (free-living conditions) over 56 days.

No differences existed in lean mass, fat mass, or weight; nor were any trends noted. A decrease in circulating TNF-a was noted with both CLA treatments, and all other parameters came back statistically insignificant.