Studies related to DNA Damage and Curcumin

Curcumin Protects DNA Damage In A Chronically Arsenic-exposed Population Of West Bengal

Effect Decrease
Trial Design Double blind
Trial Length 6+ Months
Number of Subjects 286
Sex Both Genders
Notes for this study:
Oral ingestion of 500mg (20:1 curcumin:piperine combination) twice a day for 6 months was able to preserve a fair bit of DNA integrity and protect the body from further Arsenic-induced DNA damage in rural areas of india with high arsenic exposure via drinking water.

The body's anti-oxidant system also somewhat normalized.

No significant effect on protein carbonylation processes from curcumin, both glutathione enzymes (reductase and peroxidase) were induced, with SOD induced during months 5-6 only.