| Effect | Decrease |
| Trial Design | Double blind |
| Trial Length | 6+ Months |
| Number of Subjects | 100 |
| Sex | Both Genders |
| Age Range | 45-64 |
| Body Types | Overweight, Average |
Curcumin, dosed at 1,000mg MERIVA (curcumin bound to phosphatidylcholine) taken in two divided dosages of 500mg, was safe and effective over a period of 8 months in alleviating clinical and biochemical symptoms of osteoarthritis in a population of middle-aged (43+/-2) persons with osteoarthritis.
Reductions were noted in IL-6 (27%), IL-1b (65%), and cell adhesion factors.
