Studies related to Fructosamine and Curcumin

Curcumin And/or Omega-3 Polyunsaturated Fatty Acids Supplementation Reduces Insulin Resistance And Blood Lipids In Individuals With High Risk Of Type 2 Diabetes: A Randomised Controlled Trial

Effect None
Values (umol/L change). Placebo: 2.2 (14.7). Curcumin: 0.8 (13.3)
Trial Design Randomized trial
Trial Length 1-6 months
Number of Subjects 81
Sex Both Genders
Age Range 30-44, 45-64, 65+
Body Types Obese, Overweight
Notes for this study:
In a randomized, double-blind, placebo-controlled trial, 81 participants with insulin resistance who were at a high risk for type 2 diabetes were allocated into roughly equal groups to take 1,000 mg of phytosomal curcumin, 1.2 g of DHA + EPA, the combination, or placebo for 12 weeks.

The primary outcomes were measures related to glucose control, primarily HbA1c, and including fasting glucose, fasting insulin, and insulin sensitivity. The curcumin group didn't see a statistically significant change in Hba1C or fasting glucose compared with placebo. Serum insulin and insulin resistance were reduced significantly in the curcumin group compared with placebo.

Triglycerides, atherogenic index and InsuTAG were significantly reduced compared with placebo in the curcumin group, but HDL was unaffected. Statistical comparisons between specific groups were not made available for the other measures, but white blood cells, lymphocytes, and monocytes were significantly reduced compared with the baseline in the curcumin group.