Highly Bioavailable Micellar Curcuminoids Accumulate In Blood, Are Safe And Do Not Reduce Blood Lipids And Inflammation Markers In Moderately Hyperlipidemic Individuals
Notes for this study:
||(ug/L). Placebo: before 145 ± 15, after 138 ± 151. Curcumin: before 150 ± 161, after 142 ± 160
|Number of Subjects
||18-29, 30-44, 45-64, 65+
||Obese, Overweight, Average
In a randomized, double-blind, placebo-controlled crossover trial, 42 participants with moderate hyperlipidemia were assigned to take 294.2 mg of micellar curcuminoids or placebo daily for 6 weeks, with 4 weeks of washout between the two conditions.
When taking curcumin, there was no statistically significant difference between groups for total cholesterol, triglycerides, LDL-C, HDL-C, c-reactive protein or IL-6 levels. There was also no statistically significant difference betwen groups for fasting glucose, insulin, or insulin resistance, and no differences in iron metabolism, body weight, or the liver enzymes AST and ALt.