Studies related to Portal Hypertension and Cocoa Extract

Postprandial Effects Of Dark Chocolate On Portal Hypertension In Patients With Cirrhosis: Results Of A Phase 2, Double-blind, Randomized Controlled Trial

Effect None
Trial Design Double blind
Trial Length 24 hours
Number of Subjects 22
Sex Both Genders
Age Range 45-64
Notes for this study:
In patients with liver cirrhosis (who, after eating a meal, experience decreases in systemic blood pressure due to their low blood flow in the liver) who are given cocoa with a test meal, when compared to white chocolate there appears to be about a halving of the refractory decrease in blood pressure from the meal thought to be indicative of better blood flow in the liver.

Despite the improvements in the refractory blood pressure (HPVG), there was no difference in portal vein or total blood flow while hepatic artery pressure was similar between groups.